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Any concerns about the copper have been disproved but if you really

Started by Space 38 replies 4 people Last activity Apr 9, 2026

Mar 4, 2026 #22
Blah blah blah, you're talking to talk.
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Mar 10, 2026 #24
GHK selectively transports copper to the tissues it's needed, it remains bound to "excess copper". That being said, high dose injections can cause tissue damage locally.
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Mar 14, 2026 #25
I've already told you how GHK works. 15% of a 2mg injection is not dangerous.
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Mar 16, 2026 #27
Can't post studies here unfortunately. Google the research using biotinylated GHK on rat wounds showed a ninefold increase in copper concentration at the site of injury.
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Mar 17, 2026 #28
It's going to blow your mind when you find the research demonstrating very high elevations of copper in metabolically active tissues, and not other tissues. I'm sure you'll say that's a mechanism and not an outcome, but it indicates tissue selectivity.
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Mar 27, 2026 #30
Fuck I just closed the window lmao one sec
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Mar 28, 2026 #31
GHK clearly demonstrates targeted delivery in metabolically active tissues, not all tissues non-selectively.
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Mar 30, 2026 #32
It also delivers copper to these cells without releasing free copper ions which prevents oxidative damage.
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Mar 31, 2026 #33
If it was to release free copper ions, you'd be in trouble. That'll damage cell structures and shit
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Apr 2, 2026 #34
Excerpt from another paper: Many researchers proposed that, at the physiological pH, GHK-Cu complexes can form binary and ternary structures which may involve amino acid histidine and/or the copper binding region of the albumin molecule. Lau and Sarkar found also that GHK can easily obtain copper 2+ bound to other molecules such as the high affinity copper transport site on plasma albumin (albumin binding constant log10 = 16.2 versus GHK binding constant 16 log10 = 16.44). It has been established that copper (II) redox activity is silenced when copper ions are complexed with the GHK tripeptide, which allows the delivery of nontoxic copper into the cell [12–14].
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Apr 3, 2026 #35
What's that last fucking sentence say? Lol
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Apr 9, 2026 #37
Bioavailable copper is what dictates homeostasis. You have to be exposed to excess bioavailable copper for homeostasis to be affected. If free copper is high, you're in trouble. This is why it's reallllllly ill-advised to arbitrarily use copper supplements or zinc supplements without concern for dosing and ratios.
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